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In this community, professionals share information regarding the clinical, programmatic and community-oriented aspects of early diagnosis, treatment and prevention of multi-drug-resistant tuberculosis (MDR-TB). Members also use this forum to promote universal access to quality care for MDR-TB.

Community moderators

Masoud Dara, MD - WHO Europe - EURO Christopher Gilpin, PhD, MPH - World Health Organization - WHO Dylan Tierney, MD, MPH - Brigham and Women's Hospital, Division of Global Health Equity
MSF sounds alarm on DR-TB practices and policies dangerously out of step

Médecins Sans Frontières (MSF) has today released a new report that looks at a survey of TB diagnostic and treatment practices in eight countries (Brazil, India, Kenya, Myanmar, Russian Federation, South Africa, Uzbekistan and Zimbabwe), takes a hard look…

By Joanna Keenan on 30 Oct 2014 0 Recommendations 0 Replies
MSF at the Union Conference

Awessome !

By Joanna Keenan on 27 Oct 2014 0 Recommendations 2 Replies
Recent recurrence of TB with hydropneumothorax

Dear Doctor, As per her 2 x-rays... 1)It is necessary to Insert an ICT as it will help in draining the intra Pleural Fluid out 2) Continues Spiro metric Exercises as it will help in lung expansion 3) Antibiotics 4) Consider for early VATS debridment if…

By Rakesh Biswas MD on 25 Oct 2014 0 Recommendations 2 Replies
Pleural TB

Enviado a partir do meu smartphone BlackBerry 10.

By Dylan Tierney, MD, MPH on 24 Oct 2014 1 Recommendations 31 Replies
SAVE THE DATE: MSF SYMPOSIUM at Union Lung Conference

SAVE THE DATE: MSF SYMPOSIUM at Union Lung Conference Changing the status quo in TB drug and regimen R&D WHAT: Changing the status quo in TB drug and regimen R&D A symposium sponsored by MSF at the 45th Union World Conference on Lung Health Agenda Ø…

By Joanna Keenan on 16 Oct 2014 0 Recommendations 0 Replies
Cutaneous MDRTB - management?

At face value, it seems like the diagnosis in this case is still somewhat in question. While cutaneous MDR-TB is possible, it would be unusual in a patient with what seems like relatively limited exposure to MDR-TB contacts (unless he was doing something…

By Natalie Lorent on 15 Oct 2014 0 Recommendations 6 Replies
How can we Spiked M. tuberculosis into sputum

I would suggest brief sonication 30 sec x 3 times, without heat to break MTB clumps. It really helps. Please note that GeneXpert detects intact MTB cells (live and dead). Autoclaving will lyse the cells so not recommended. Also please check internal…

By Dossegnaw Aragaw on 15 Oct 2014 0 Recommendations 8 Replies
Moxifloxacin critical concentration

In 2012, WHO convened an Expert Group to review and update the critical concentrations for both first- and second-line anti-TB agents. Based on experience and limited evidence from several TB supranational reference laboratories, the concentrations were…

By Maha Farhat on 10 Oct 2014 0 Recommendations 1 Replies
Treatment of Mono and Poly drug Resistance

I will request all to share heir experience and related evidence for Treatment of Mono and Poly drug Resistance in their setup.

By Prof.Matiur Rahman on 09 Oct 2014 0 Recommendations 0 Replies
the future of TB diagnostics

Dear Dylan, dear Reader Thank you for sharing these two important documents. There are many challenges in developing diagnostic products that meet patient needs (as described in the WHO, FIND, McGill, MSF, New Diagnostics Working Group and Stop TB…

By Dylan Tierney, MD, MPH on 07 Oct 2014 0 Recommendations 1 Replies
New Medicines and Novel Approaches for MDR-TB

Thank you so much Amoud for your very kind and helpful response which actually cleared number of questions but opened up for more queries. However, I would wait to see more details when the study is published later on. With this I cc. Dr. Caminero for…

By Masoud Dara, MD on 18 Mar 2014 6 Recommendations 92 Replies
The Updated WHO Policy on Xpert MTB/RIF assay: What is New and How it May Support Implementation

Dear all I wander the one who answer the question of the training of GeneXpert. Belayneh

By Fuad Mirzayev on 16 Jan 2014 2 Recommendations 202 Replies
Creating Opportunities for Health Scientists in Disease Endemic Countries

Hi Chris, I was not aware of AfricaOER - looks like a great resource. Some time ago (perhaps 4-6 months), there was a discussion on the Global Public Health group on Linked In about open resources in public health - and a lot were listed. However, it seems…

By Sungano Mharakurwa on 09 Aug 2013 0 Recommendations 75 Replies
Lessons Learned in India: E-Compliance for TB Treatment by Operation ASHA

Hi Ruth, many thanks for this idea and if you'd like to work with us to plan a virtual Expert Panel on this topic happy to work with you on this! Please email me at or To all, we're…

By Sophie Beauvais on 05 Jul 2013 5 Recommendations 75 Replies
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