In this community, professionals share information regarding the clinical, programmatic and community-oriented aspects of early diagnosis, treatment and prevention of multi-drug-resistant tuberculosis (MDR-TB). Members also use this forum to promote universal access to quality care for MDR-TB.
Dear Colleagues, UCSF is excited to accept applications to the HEAL Initiative, an innovative two-year post-residency global health fellowship dedicated to equipping physicians and nurse practitioners with the knowledge and expertise needed to serve effectively in resource-limited settings, both internationally and in the U.S. We currently have nearly 50 HEAL ... read more
Posted on behalf of Dr David Dolinger, FIND: Dr England makes a very good point about the importance of understanding the capacity and limitations of each manufacturer’s assay, notably the differences in various epidemiological contexts. FIND and partners have a number of ongoing projects and collaborations, including a systematic review ... read more
Dear Ranjan, From the package insert HAIN MTBDRplus Version 2.0: Analytical Sensitivity (p.11)…”For the determination of analytical sensitivity of the GenoType MTBDRplus, ten replicates of MTBC-negative sputum samples were spiked with four BCG culture dilutions (1000, 500, 200, 160 and 100 bacteria/ml, respectively), extracted once using the GenoLyse @ kit ... read more
Dear Monica, There are several reasons for TTP <4 days. a) large number of mycobacterium in the sample (SS grade high positivity) b) Non TB mycobacterium present in patient sample (fast growing NTM) c) Mixed sample NTM and TB bacilli (NTM outgrows the TB bacilli) - You must confirm MTB ... read more
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