Dr. Zarir F. Udwadia of P. D. Hinduja National Hospital and Medical
Research Centre in Mumbai, India, described cases of TDR-TB in Clinical
Infectious Diseases last December (
All four patients were tested as resistant to all first and second line
drugs. Furthermore, it was found that three of them "had received erratic,
unsupervised second-line drugs, added individually and often in incorrect
doses, from multiple private practitioners (mean, 4 physicians during a
18-month period) in an attempt to cure their multidrug-resistant (MDR)
Udwadia concludes by urging "patients with MDR tuberculosis only be treated
within the confines of government-sanctioned DOTS-Plus programs to prevent
the emergence and spread of this untreatable form of tuberculosis."
Thoughts? Thank you.