MDR-TB Treatment & Prevention

Attached resource:

• Global Tuberculosis Control: epidemiology, strategy, financing (WHO Report 2009); with Short Update (download, 1.5 MB)

  Summary: For Full Report: http://www.who.int/tb/publications/global_report/2009/en/ For Short Update: http://www.who.int/tb/publications/global_report/en/index.html For Key Points: http://www.who.int/tb/publications/global_report/2009/key_points/en/index.html For Key Points in 6 Languages (Arabic, Chinese, English, French, Russian and Spanish): http://www.who.int/tb/publications/global_report/2009/key_points_download/en/... Summary: On March 24, in honor of World TB Day, The World Health Organization released its 2009 Report on Global Tuberculosis Control. This is the 13th annual report in the series, which aims to provide a comprehensive, up-to-date assessment of the TB epidemic and progress in controlling the disease at global, regional and country levels. This year’s report investigates the data in context of the global targets set for 2015. The primary source of data for this report is the WHO’s standard TB data collection form, which was submitted by 196 countries and territories, which account for 99.7% of the world’s population. The document includes estimates of the burden of MDR-TB, which is presented by country and disaggregated by smear status, in ANNEX 3. Information about the methodology of collecting this data is presented on pages 10-11. Section 2.3.2 (pg. 49-54) deals with diagnosis and treatment of MDR-TB, and includes information about progress against Global Plan targets. Summary of Section 2.3.2: - 510545 cases of MDR-TB in 2007 - These cases are unevenly distributed, with 27 countries (15 of which are in Eastern Europe) accounting for 85% of cases - Diagnosis of MDR-TB requires availability and use of DST (drug susceptibility testing) services - The GLC was established in 2000, with the purpose of enhancing access to quality assured second-line drugs at competitive prices and ensuring that treatment was provided according to WHO guidelines. In 2007, the 3 681 patients who were treated in GLC-approved projects represented 0.7% of estimated MDR -TB cases. - Targets set in the Global Plan are far above country projections in the three regions with the highest number of MDR -TB cases: the European Region, the South-East Asia Region (principally India) and the Western Pacific Region (where most cases are in China). In the African Region and the Region of the Americas, projections of the number of patients treated for MDR -TB treatment are ahead of Global Plan targets. Attached here is the document without annexes. The document with annexes is large (7.28 Mb), and is accessible at the link listed here. The key points of the document are available in the six UN languages (English, Spanish, Arabic, Chinese, French, Russian) at the same link. TABLE OF CONTENTS Key points Introduction CHAPTER 1: EPIDEMIOLOGY Goals, targets and indicators for TB control TB incidence, prevalence and mortality Improving measurement of progress towards the 2015 impact targets: the WHO Global Task Force on TB Impact Measurement Case notifications Case detection rates Outcomes of treatment in DOTS programmes Progress towards reaching targets for case detection and treatment success Summary CHAPTER 2: STRATEGY Data reported to WHO in 2008 DOTS expansion and enhancement Address TB/HIV, MDR -TB, and the needs of poor and vulnerable populations Contribute to health system strengthening based on primary health care Engage all care providers Empower people with TB, and communities through partnership Enable and promote research Summary CHAPTER 3: FINANCING Data reported to WHO in 2008 NTP budgets, available funding and funding gaps Total costs of TB control Comparisons with the Global Plan Budgets and costs per patient Expenditures compared with available funding and changes in the number of patients treated Global Fund financing Funding gaps and the global financial crisis Summary CONCLUSIONS Annex 1: Profiles of high-burden countries Annex 2: Methods Annex 3: The Stop TB Strategy, case reports, treatment outcomes and estimates of TB burden Annex 4: Surveys of tuberculosis disease and availability of death registration data at WHO, by country and year An editorial discussing the findings released in this report was published in the Lancet here: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)60662-0/ful... Source: World Health Organization - WHO Publication Date: March 24, 2009 Languages: Arabic, Chinese, English, French, Russian, Spanish Keywords: Annual Report, General Resources, Publications & Research, who Preview