Scaling Up Programmatic Management of Drug-Resistant Tuberculosis: A Prioritized Research Agenda
Summary Points:
* The World Health Organization calls for massive scale-up of programmatic management of drug-resistant tuberculosis in resource-limited settings.
* Several technical and operational barriers impede the achievement of this scale-up.
* A research agenda, developed by the Stop TB Partnership, identifies the most important barriers and prioritizes the research questions to be addressed in order to overcome these barriers.
* Research priorities include: new and improved tools for drug resistance testing; clinical trials of simplified and shorter second-line treatment regimens; new and improved strategies for diagnosis of drug-resistant tuberculosis, treatment adherence, and infection control; understanding of the geographic variations in occurrence of drug resistance; and clinical trials of prophylactic treatment of contacts of patients with drug-resistant tuberculosis.
Attached resource:
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Scaling Up Programmatic Management of Drug-Resistant Tuberculosis: A Prioritized Research Agenda (external URL) Link leads to: http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0050150&ct=1
Summary: Summary Points:
* The World Health Organization calls for massive scale-up of programmatic management of drug-resistant tuberculosis in resource-limited settings.
* Several technical and operational barriers impede the achievement of this scale-up.
* A research agenda, developed by the Stop TB Partnership, identifies the most important barriers and prioritizes the research questions to be addressed in order to overcome these barriers.
* Research priorities include: new and improved tools for drug resistance testing; clinical trials of simplified and shorter second-line treatment regimens; new and improved strategies for diagnosis of drug-resistant tuberculosis, treatment adherence, and infection control; understanding of the geographic variations in occurrence of drug resistance; and clinical trials of prophylactic treatment of contacts of patients with drug-resistant tuberculosis.Source: PLoS Medicine
Publication Date: July 8, 2008
Language: English
Keywords: Publications & Research
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