Evolutionary concepts as applied to malaria treatment and prevention
For an excellent synopsis of how evolutionary forces such as natural selection and adaptation "shape" infectious diseases in humans esp. with regard to malaria treatment (parasite chemotherapeutic resistance) and transmission (insecticide resistance), I'd like to point the community to Andrew Read's recent TEDMED talk at the 2012 conference in Washington DC. I would also like to share an excellent blog post in PLoS Biology's Biologue on how "leaky" vaccines can lead to selection of higher virulence in rodent malaria models. See below for links. -MR
Andrew Read @TED MED 2012: http://youtu.be/cvXc9aMF6CA
PLoS Biology Biologue: http://blogs.plos.org/biologue/2012/07/31/could-vaccines-breed-super-virulent...