Injectable Treatments for Severe Malaria (original post by Vince Waite: 24 Oct 2010)
Recently I was in Ghana and their protocol for Cerebral Malaria treatment did not include the 20mg/kg loading dose for Quinine which I have always used. I understand there is some literature that states that there is not a clear benefit to the loading dose. What are others doing? Is this the trend?
An additional question relates to Artemether IM dosing. This drug is now available in the rural areas of Ghana. Is there a clear benefit of the IM Artemther over Quinine? Artemether is still in low supply as compared to Quinine. We started using it when there was not a good response to Quinine after 48hrs. Does this make sense? (IV Artesunate is not available)
Thanks for considering this query?