Endemic Non-Communicable Diseases
Availability of Low-Cost Diagnostics for Malaria, Typhoid, Cholera, Anemia, Fetal Health, and Cardiovascular Diseases
Started by Michael Chang on 18 Mar 2011
Last edited by Robert Szypko on 28 Jul 2011
Hi everyone,
I am an MIT graduate student currently in India working with a local healthcare nonprofit based out of Hyderabad. The organization has asked me to research low-cost diagnostics that can be easily and reliably used by semi-literate village health workers. These health workers are equipped with basic medicines, training, and a cell phone to communicate with doctors in larger cities. There is no refrigeration, no internet, and limited electricity.
We are focusing our search on the following diseases:
-Malaria
-Typhoid
-Cholera
-Anemia
-Fetal Health
-Malnutrition
-TB
-Diabetes
-Cardiovascular Diseases
If anyone knows of any diagnostics either currently available or in the R&D pipeline, that would be very helpful. Or if you could direct me to some resources or contacts that would also be useful.
Many thanks,
Michael
Keywords: Cardiovascular Diseases Children & NCDs Diabetes diagnostics

Kate Armstrong
Dear Michael,
expand commentI would like to highly recommend visual blood glucose strips for measuring blood glucose levels in Diabetes. The strips are very cheap (about 10% of the cost of meter strips, and that doesn't even include the cost of the meters, batteries (usually very small / flat / circular / unusual and expensive types and hard to find in remote provinces to replace flat ones) and calibration issues) and accurate and can be used not only for initial screening but also for affordable ongoing monitoring.
We have shared these strips with families of children living with T1DM in Vietnam - they have been well accepted (the crowds around the demonstration tables were 10 deep at the Club meetings until we found better ways to show how to use them), visual instructions show how to use them and families really love the price. It's not official, but you can also cut the strips in half (lengthways) and get two tests for the price of 1... We have been told that some people cut them up even thinner (++), but perhaps more testing would be needed to see at what point cutting needs to stop! :) The strips do not need refrigeration, are light-weight and ...
1:51 AM, 18 Mar 2011 | Permalink
Smitha Gudapakkam
Hi Michael,
I would recommend that you take a look into http://www.dfa.org/index.html - Diagnostics for All. I heard their CEO speak at the Unite for Sight Global Health Conference at Yale University this year. They are developing low cost point of care diagnostic. Currently they are testing the technology for Liver based diseases but they have the technology to diagnose TB, Malaria, HIV, etc.
Thanks
Smitha
12:46 PM, 19 Jul 2011 | Permalink
Sandeep Saluja
I would be happy to be a part of a trial to assess them.
9:03 PM, 19 Jul 2011 | Permalink
Matthew Stewart
Dear Michael,
Diagnostics for All is non-profit dedicated to creating low-cost, easy-to-use, point-of-care diagnostics designed specifically for resource limited settings. Our devices require minimal training to use, practically no sample preparation, no electricity or additional equipment to process a sample, and easy visual readout. Our most advanced diagnostic to date is a liver function test and our platform can be adapted to perform other clinical assays and disease detection.
We greatly appreciate Smitha's referral, however, we do not currently have diagnostic tests ready for testing for the diseases listed in your initial posting. We are currently seeking funding to develop tests for these illnesses and hope to have them in the pipeline in the near future.
Best regards,
Matthew
11:50 AM, 20 Jul 2011 | Permalink
Sandeep Saluja
Mathew,that is interesting.Would like to interact with you directly to learn more.
5:32 PM, 20 Jul 2011 | Permalink
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