Dr. Daniela Cirillo, MD, PhD
About Dr. Daniela Cirillo, MD, PhD
Member of the TB Supra National Laboratory Network for TB
Head, Emerging Bacterial Pathogens Unit, San Raffaele Scientific Institute
Role(s) / Profession(s)
- Researcher
Organization
- Fondazione San Raffaele Del Monte Tabor - San Raffaele Scientific Institute
- Istituto Superiore di SanitÃ
Work Location(s)
- Italy
Language(s)
- English
- Italian
Dr. Daniela's Communities
Recent Contributions
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Dr. Daniela Cirillo, MD, PhD replied to "Expert Panel Dec. 10-14: Scaling-up GeneXpert MTB/RIF" in the MDR-TB Treatment & Prevention community.
The most probable diagnosis is NTM. It is very unlikely that your strains are false negative for two different tests
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Dr. Daniela Cirillo, MD, PhD replied to "Expert Panel Dec. 10-14: Scaling-up GeneXpert MTB/RIF" in the MDR-TB Treatment & Prevention community.
I would like to underline a different problem: availability of xpert and reagents but very limited use of the test and request s by the clinicians. I believe that efforts should be made to educate and increase the knowledge and the confidence on the test
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Dr. Daniela Cirillo, MD, PhD replied to "Expert Panel Dec. 10-14: Scaling-up GeneXpert MTB/RIF" in the MDR-TB Treatment & Prevention community.
Der Dr Clement, unfortunately some false positive and false negative are expected in the best scenario and the best tests. The patient has received an effective treatment anyway so I don't see a big ethical issue. Patients with NTMs have been treated for MDR-TB when the only test available to ...
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Dr. Daniela Cirillo, MD, PhD replied to "Expert Panel Dec. 10-14: Scaling-up GeneXpert MTB/RIF" in the MDR-TB Treatment & Prevention community.
In addition to the comment of Fuad I would like to add that it is important to diagnose MDR-TB even in the absence of treatment because infection control measures can be enforced and patients could be instructed to follow a behavioral etiquette in order to prevent new infections in hospital/ ...
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Dr. Daniela Cirillo, MD, PhD replied to "Expert Panel Dec. 10-14: Scaling-up GeneXpert MTB/RIF" in the MDR-TB Treatment & Prevention community.
Treatment for MDR should be started as soon as possible. With or without INH is under discussion but clear evidence are missing. Rif resistance should be reconfirmed when and where it is feasible. LPA is the fastest way to do it. Regarding DST sensitivity tests when the strains are grown ...
Recent Recommendations
- None at this time.