Gabit Ismailov

Gabit Ismailov replied to "Viability of TB organisms in air." in the TB Infection Control community.

Dear Dr Nardell, There is a rather old but informative publication by Dr John Weinzirl [1] studying the action of sunlight on MTB. In his experiments MTB was killed in 2-10 min by direct sunlight when planted upon glass or paper. Kind regards, Dr Gabit Ismailov Medical Officer Tuberculosis Control Programme WHO/EURO [1] Weinzirl, J. (1906). "The Action of Sunlight upon Bacteria with Special Reference to B. tuberculosis." Public Health Pap Rep 32(Pt 2): 128-153.

Gabit Ismailov replied to "TB treatment" in the MDR-TB Treatment & Prevention community.

Dear Masoud, Thank you for this kind intervention. The published reviews of Dr Menzies were indeed often quoted and referenced in our intense discussions this week when revising draft treatment protocol in Azerbaijan. One particular point (of disagreement) was related to the choice of treatment regimen for new PTB patients with lab confirmed susceptibility to all first-line drugs. WHO recommends standard Cat 1 regimen [2HREZ/4HR(E)] with strong degree of evidence. However, the national protocol working ...

Gabit Ismailov replied to "TB treatment" in the MDR-TB Treatment & Prevention community.

Dear colleagues, I would like to add one important point of clarification to the above posting. The issues in question relates to treatment protocol for new fully susceptible patients with radiological findings of extensive PTB (more than 1 lobe affected of PA CXR). Regards, Dr Gabit Ismailov Medical Officer WHO/Europe

Gabit Ismailov replied to "TB treatment" in the MDR-TB Treatment & Prevention community.

Dear Alexander, WHO recommendations are based on the quality of the evidence, values, and costs, as well as judgements about trade-offs between benefits and harm. The quality of the evidence is assessed according to the GRADE methodology (Atkins et al. 2004). For high-quality evidence further research is unlikely to change confidence in the estimate of effect. A 6-mo R-containing regimen for all (especially fully susceptible) new PTB cases irrespective of severity of disease is a ...