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By Diane Nyole | 04 May, 2011

Does the operational temperature of the Xpert machine affect the results outcome? why was it necessary to capture the operational temperature range in south africa?

Attached resource:
  • Evaluation of Xpert MTB/RIF in Decentralized Settings (external URL)

    Link leads to: http://download.thelancet.com/pdfs/journals/lancet/PIIS0140673611604388.pdf?id=4d037fefcb72946c:-6ed9353d:12f9b9bdfb0:-17731303987864426

    Summary: Feasibility, diagnostic accuracy, and effectiveness of decentralized use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study. The Lancet 2011;377:1495-1505.

    This clinical study evaluates the performance of the Xpert MTB/RIF in decentralized clinics in both peri-urban and urban areas. As the article notes, it is important to evaluate the diagnostic tool in the setting in which it will be used since initial evaluations carried out in ideal settings, such as reference laboratories, might be misleading. The results of this study demonstrate that the performance and accuracy of the Xpert MTB/RIF was similar to the initial clinical trial (NEJM reading above) confirming that the test can be used in low-resource settings for early and accurate diagnosis.

    Full text available to registered users of the Lancet website (free registration)

    Source: The Lancet

    Language: English

    Keywords: diagnostics, Laboratory, Monitoring & Evaluation, Publications & Research


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