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Is there role of kidney biospy with loss of CMD and reduced size? like incase of young patient with no diabetes or hypertension.
Chronic kidney disease can be diagnosed by imaging and blood parameter.UsG showing loss of CMD, contracted kidney with increased echogenecitysuggestive of CKD irrespective of the etiology and invariably doesnotrequire biopsy to prove CKD . Whatever the etiology , final outcome isglomeruolosclerosis, interstitial atropy, and tubular atrophy , which arethe core histopathological features of CKDOnly in certain situation and in certain center , where cause of CKD is notknown at occasion , renal biopsy is performed to exclude the FSGS (recurrence rate in transplanted kidney is quite high in non genetic FSGS)as the primary cause of CKD for the preparation of transplantation infuture. I dont think so there would be additional advantage on doingbiopsy when you already has imaging and blood parameter report suggestiveof CKD.Any other opinion please share on this matter