Peter Cegielski

Recent Contributions

Reply to [ARCHIVED] Advancing Care Delivery: Driving Demand and Supply of Diagnostics

Sept. 29, 2015
Thank you to all of the participants for a very informative and interesting discussion. Let me add another dimension to this topic. There are at least 2 very different types of regulations affecting diagnostic products and diagnostic tests. First, there are regulations that affect commercially available diagnostic products per se, ...

Reply to [ARCHIVED] Anti-TB Drugs and Arrhythmia: Theoretical Concern or Real Risk?

July 9, 2015
Just to clarify, I meant the mycobacterial efflux pumps can make some of the anti-TB drugs less effective (by lowering their intracellular concentration) and may lead to drug resistance. Blocking the efflux pumps would make the anti-TB drugs more effective and may prevent drug resistance. Again, this is hypothetical.

Reply to [ARCHIVED] Anti-TB Drugs and Arrhythmia: Theoretical Concern or Real Risk?

July 9, 2015
Very interesting discussion! Thank you to everyone participating, asking and answering these enlightening and important questions. My question has to do with concurrent use of a drug like verapamil that is sometimes used for cardiac arrhythmias. Verapamil (and other ion channel blockers) has an interesting theoretical potential benefit in that ...


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